Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00165Aripiprazole--
BADD_D00166Aripiprazole lauroxil--
BADD_D00167Armodafinil--
BADD_D00168Arsenic--
BADD_D00169Arsenic trioxide0.000533%
BADD_D00170Articaine hydrochloride--
BADD_D00176Atazanavir--
BADD_D00178Atenolol--
BADD_D00179Atezolizumab--
BADD_D00181Atomoxetine hydrochloride--
BADD_D00186Atovaquone--
BADD_D00189Atropine0.000687%
BADD_D00192Avanafil--
BADD_D00193Axitinib--
BADD_D00194Azacitidine--
BADD_D00195Azathioprine0.017950%
BADD_D00198Azelastine--
BADD_D00200Azilsartan--
BADD_D00201Azilsartan kamedoxomil--
BADD_D00202Azilsartan medoxomil--
BADD_D00203Azithromycin0.000189%
BADD_D00206Aztreonam--
BADD_D00209Baclofen--
BADD_D00210Balsalazide--
BADD_D00211Balsalazide disodium--
BADD_D00214Basiliximab--
BADD_D00217Beclomethasone--
BADD_D00218Beclomethasone 17-monopropionate--
BADD_D00219Beclomethasone dipropionate0.001637%
BADD_D00223Belatacept--
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